Drosophila with cGLR1 mutations behaved similarly to STING mutants, with a decrease in the activation of various STING-associated genes (Srg1, Srg2, and Srg3), and an increase in infection by Kallithea virus (a DNA virus) and Drosophila C virus (an RNA virus) as well as reduced survival. Here, STING1 is linked to infection.