There was a significant negative correlation between frequency of CD8+ TN and age in MM and Severe groups (Spearman r=-0.6059, p=0.0107 and r=-0.6249, p=0.0107, respectively) (Figure 1D) and a significant positive correlation between frequency of CD8+ TEF and age (r=0.5594, p=0.0324 and r=0.5556, p=0.0274) (Figure 1E) in the MM and Severe groups. The gene discussed is CD8A; the disease is Miyoshi myopathy.