PLOD1 and metabolic disease: Compared with those in the control group, the body weight, serum T, and Glu significantly increased in the model group (p = 0.000, 0.004, and 0.04); FSH, LH, HOMA-IR, and LPS had an increasing trend (p > 0.05); HOMA-beta had a downward trend (p > 0.05), showing the change of endocrine and metabolic disorders.