HOTAIR and breast cancer: LncRNA HOX Transcript Antisense Intergenic RNA (HOTAIR), as an oncogenic trans-acting lncRNA, is elevated in multiple cancers [5] and plays a regulatory role in the growth, apoptosis, migration and invasion of carcinoma [6,7].However, the underlying molecular mechanism of HOTAIR in BC remains not yet fully elucidated.HOTAIR regulates miR-130a-3p expression in hepatocellular carcinoma cells [8].