Previous studies have described stochastic “go or grow” patterns in highly infiltrative GBM, with proliferation and invasion being characterized as mutually exclusive.[41, 42] Due to the increased invasion of GB3‐RFP cells in triculture condition, we further interrogated GB3‐RFP cell proliferation using both EdU and Ki‐67 staining kits and analyzed the overlap of positive expression with RFP within the stromal region of the platform. This evidence concerns the gene MKI67 and glioblastoma.