In a recent study, among 16 patients with MODY who were offered treatment switch after genetic diagnosis, nine (six HNF1A, three KCNJ11) were stably switched from insulin to oral sulfonylurea but seven (three HNF4A, two ABCC8 and one each HNF1A and KCNJ11) had to restart insulin [32]. The gene discussed is KCNJ11; the disease is MODY.