As CTNNB1 plays critical roles in adherens junction formation and WNT signalling to regulate cell proliferation and migration15, we first performed gene set enrichment analysis (GSEA) by comparing two groups of the tumour samples: (1) tumour samples with over-spliced CTNNB1 3′ SP and (2) the remaining tumour samples. Here, CTNNB1 is linked to neoplasm.