To elucidate the role of SERINC genes during SARS-CoV-2 infection, we initially examined the levels of all the members of the SERINC protein family (SERINC1-5) in total lung tissue RNA from three donors and Calu-3 cells, a human pneumocyte cell line, as pneumocytes are natural targets of SARS-CoV-2 infection18. The gene discussed is SERINC1; the disease is COVID-19.