AKR1C1 and breast cancer: We identified BC causing 13 DEGs (AKR1C1, IRF9, OAS1, OAS3, SLCO2A1, NT5E, NQO1, ANGPT1, FN1, ATF6B, HPGD, BCL11A, and TP53INP1) as the KGs by using the five topological measures in the PPI networking results.