Among Th2 cytokines in the mouse lung, we found that the levels of all four marker cytokines (IL-4, IL-6, IL-10, and IL-13) progressively increased with infection time (Fig 6A); similarly, the levels of IL-6, IL-10 and IL-13 were upregulated in the mouse brain (S4B Fig). The gene discussed is IL4; the disease is infection.