In addition, we performed a multivariate analysis for the 4 variables with p < 0.20 in the univariate analysis, extracting a residual tumor status of R1 (HR 2.687, 95% CI 1.487 to 4.855, p = 0.00106) and high SPRR1A expression (HR 1.706, 95% CI 1.018 to 2.862, p = 0.0427) as significant risk factors. Here, SPRR1A is linked to neoplasm.