To identify the gene expression profiles in PDAC with a high SPRR1A expression, we compared the gene expression profiles between the high- (n = 59) and low- (n = 59) SPRR1A-expression groups utilizing the TCGA-PAAD dataset stratified into 3 groups as in the same method as in the prognostic analyses in Fig 3. The gene discussed is SPRR1A; the disease is pancreatic adenocarcinoma.