APOE and Alzheimer disease: Individuals with preclinical stages of AD and APOE4 carriers who carry an elevated risk of developing AD show increased alpha power and synchrony in select regions including medial frontal and posterior parietal cortices (Cuesta et al., 2015; Nakamura et al., 2018; Pusil et al., 2019), whereas in patients with AD dementia syndrome the alpha power and long-range synchrony are reduced (Sami et al., 2018; Ranasinghe et al., 2020).