UBE2A, UBE2C, UBE2I, UBE2L3, UBE2O, UBE2Q1, UBE2S, UBE2V2, UBE2W and UBE2Z levels were significantly upregulated in patients with HNSCC (Figure 1 and Figure S1). Here, UBE2S is linked to head and neck squamous cell carcinoma.