For example, the induction of ferroptosis in hepatocellular carcinoma cells, which has the effect of suppressing cell viability and proliferation, can be activated via the lnc-PVT1/miR-214-3p/GPX4 axis [8], TRIB2/β-TrCP/TFRC [9], or p62-Keap1-NRF2 pathways [10]. Here, GPX4 is linked to hepatocellular carcinoma.