Then, we developed a novel prognostic model on the basis of 17 ARGs (BID, ATG4B, CASP4, ZFYVE1, PRKAR1A, CAPN10, NFKB1, NPC1, TP53INP2, ULK1, MAPK1, HSPA8, EIF2S1, CDKN2A, PTEN, BAG1, and BNIP3), all of which together could be the independent prognostic indicators for ccRCC patients. The gene discussed is NPC1; the disease is nonpapillary renal cell carcinoma.