Of the 17 ARGs we previously verified, genes BID, CASP4, ZFYVE1, PRKAR1A, NPC1, TP53INP2, HSPA8, EIF2S1, and BAG1 were detected in 293T, HK2, 786-O, ACHN, and A498 cell lines and they were all rarely studied in renal cell carcinoma. The gene discussed is NPC1; the disease is hereditary clear cell renal cell carcinoma.