Numerous studies have described that methyltransferases (“writers”) [METTL3 (Vu et al., 2017), METTL14 (Weng et al., 2018), WTAP (Naren et al., 2021)], demethylases (“erasers”) [FTO (Qing et al., 2021a), ALKBH5 (Shen et al., 2020; Wang et al., 2020)], and the common m6A binding protein (“reader”) [YTHDF2 (Paris et al., 2019)] were significantly upregulated in different subtypes of AML. This evidence concerns the gene METTL3 and acute myeloid leukemia.