Along with extensive IFN-γ production in the lungs of sarcoidosis patients, the expression of cytokines, including pro-inflammatory cytokines, such as TNF, IL-12, IL-18, and IL-6, and regulatory cytokines, such as TGF-β and IL-10, has been reported to be upregulated in affected tissues (94). Here, IFNG is linked to sarcoidosis.