Among the 991 PLS1genes, we detected 19 genes (ZSCAN2, CYP26B1, DRD2, NCAN, DOC2A, CHRNA3, MED19, NUTF2, PTN, DPYD, GATAD2A, OSBPL3, DND1, ARL3, MAD1L1, HCN1, ATP2A2, SATB2, and SRPK2) that overlap with genes in the 108 gene loci (348 genes) (Schizophrenia Working Group of the Psychiatric Genomics, 2014). The gene discussed is DPYD; the disease is schizophrenia.