Histological workup revealed isocitrate dehydrogenase (IDH) wild-type-glioblastoma WHO grade IV in 29 cases, of which case no. 20 featured a giant cell component, case no. 26 was described as infiltration zone of a known glioblastoma, and histology in case no. 30 was mainly necrosis. Here, IDH3A is linked to glioblastoma.