Statins could reduce the level of cholesterol and affect the formation of lipid rafts on the cell membrane, thereby affecting the androgen receptor (AR) pathway, epidermal growth factor receptor (EGFR) pathway, luteinizing hormone receptor pathway, and others (23–25), thus inhibiting downstream signaling pathways such as AKT and JAK-STAT3 (26), and then suppressing tumor cell growth and promoting cell apoptosis. The gene discussed is AKT1; the disease is neoplasm.