To further assess the role of YAP in glucose metabolism and osteosarcoma progression in Ctsk‐Cre;Trp53f/f/Rb1f/f mice, we deleted YAP in Ctsk‐Cre;Trp53f/f/Rb1f/f mice to generate a triple‐cKO mouse model, Ctsk‐Cre;Trp53f/f/Rb1f/f/YAPf/f (triple cKO). The gene discussed is CTSK; the disease is osteosarcoma.