For instance, our DisoRDPbind [19], [20], which predicts residues that interact with proteins and nucleic acids, was recently used to study the SARS-CoV-2 proteome [21], decode functions of genes from pathogenic organisms [22], and investigate the mixed lineage leukemia 4 (MLL4) [23], heat shock factor 1 (Hsf1) [24] and mediator complex subunit 15 (MED15) [25] proteins that are associated with cancer and neurodegenerative diseases. This evidence concerns the gene MED15 and neurodegenerative disease.