Among them, fifteen were highly expressed in tumor tissues (TRIB3, ERN1, IRS1, CXCL2, TLR4, ITPR2, BCL2L11, TP53, CCL2, HMOX1, PDIA5, CXCR4, CYBB, HCP5, CASP8), and one was highly expressed in normal tissues (PDIA2) (Fig. 1B and Table 1). This evidence concerns the gene TRIB3 and neoplasm.