Among them, fifteen were highly expressed in tumor tissues (TRIB3, ERN1, IRS1, CXCL2, TLR4, ITPR2, BCL2L11, TP53, CCL2, HMOX1, PDIA5, CXCR4, CYBB, HCP5, CASP8), and one was highly expressed in normal tissues (PDIA2) (Fig. 1B and Table 1). Here, ERN1 is linked to neoplasm.