There are a number of mutations in genes encoding sarcomeric and cytoskeletal proteins, including TNNI3, ACTC, β-MHC, TNNT2, TNNC1, DES, MYH, MYL3, and CRYAB, that have been reported to be etiologically linked to RCM [5]. Here, TNNT2 is linked to cardiomyopathy, familial restrictive, 1.