While the inflammatory and nutritional status assessment using C-reactive-protein (CRP) to albumin ratio (CAR) based on serum levels of CRP and albumin (Alb) has been shown to predict prognosis of elderly patients with solid tumors4–7 and hematological malignancies treated with HSCT8, its prognostic significance in elderly patients with AML remains to be clarified. This evidence concerns the gene ALB and acute myeloid leukemia.