One such protein we identified is Cacna1a, a α1A-subunit of voltage-gated P/Q-type calcium channels (Cav2.1), which contains a mutation that causes spinocerebellar ataxia type 6 (SCA6) and episodic ataxia type 250,51. The gene discussed is SERPINA1; the disease is spinocerebellar ataxia type 6.