Cortex and hippocampal Camk2a neuron proteins enriched in glutamatergic transmission proteins and long-term potentiation (e.g., Lingo1, Homer1, Gria1) were associated with mental health disorders (schizophrenia, bipolar disease, depression, autism), neurodevelopmental disorders, essential tremor, and primary epileptic disorders (e.g., West syndrome). The gene discussed is HOMER1; the disease is major depressive disorder.