Cortex and hippocampal Camk2a neuron proteins enriched in glutamatergic transmission proteins and long-term potentiation (e.g., Lingo1, Homer1, Gria1) were associated with mental health disorders (schizophrenia, bipolar disease, depression, autism), neurodevelopmental disorders, essential tremor, and primary epileptic disorders (e.g., West syndrome). Here, LINGO1 is linked to major depressive disorder.