ALDH7A1 and head and neck squamous cell carcinoma: Patients with HNSCC and mutant ALDH7A1 (missense mutation, c.1168 G > C, rs121912707) had lower ALDH7A1 expression than those carrying ALDH7A1 wild-type [39], but in the current study, ALDH7A1 rs13182402 mutation led to increased ALDH7A1 expression.