CDKN1C and posterior cortical atrophy: We noted downregulation of CDKN1C (p57kip2) [48] and UBA7 [49] (Fig. 5B,C) and upregulation of PLK1 [50], AurkB [51] and PARPBP1 [52] (Fig. 5D–F) mRNAs in PCa tumors compared to the normal prostate epithelium.