Higher PPL expression also shown a correlation with poorer prognosis in uterine corpus endometrial carcinoma, pancreatic ductal adenocarcinoma, as well as bladder cancer, while the low expression of PPL was correlated to poor survival in ACC, SARC, and breast cancer, kidney renal papillary cell carcinoma, et al. PPL might play different roles in different types cancer. This evidence concerns the gene PPL and cancer.