We also performed TIRF with SMLM to investigate anti-cancer drugs cetuximab [25] and trastuzumab [26], to our knowledge for the first time on living human cancer cells, although correlative fluorescence microscopy and liquid phase electron microscopy have been used previously to investigate the drug lapatinib that reversibly inhibits both EGFR and HER2 [22]. This evidence concerns the gene EGFR and cancer.