It was found that the viability of CRC cells, which was initially suppressed by sh-DLEU2, was restored after further RARB silencing (Figure 6b) (SW480: 0 h: p = 0.9931; 24 h: p = 0.4837; 48 h: p = 0.0069; 72 h: p = 0.0001; HT29: 0 h: p = 0.9947; 24 h: p = 0.2835; 48 h p = 0.0013; 72 h: p < 0.0001). Here, RARB is linked to colorectal carcinoma.