The apoptosis of CRC cells was reduced after RARB downregulation (Figure 6e) (SW480: sh-DLEU2 + sh-NC vs. sh-DLEU2 + sh-RARB: p = 0.0001; HT29: sh-DLEU2 + sh-NC vs. sh-DLEU2 + sh-RARB: p = 0.0003). The gene discussed is RARB; the disease is colorectal carcinoma.