Using the PD‐L1 TC 1% cutoff, PD‐L1 positive expression (TC ≥ 1%) was linked to a higher ORR versus no expression (TC < 1%) in ESCC (24.2% vs. 6.3%) but not for BTC (5.6% vs. 11.4%) (Table 3). The gene discussed is CD274; the disease is esophageal squamous cell carcinoma.