Analysis of cytotoxicity data in the 10:1 ratio of the effector: target cells showed that the cytotoxicity of activated NK cells was significantly higher in CRC PBMCs than in normal PBMCs in all groups, i.e. the PBMC (p < 0.05), PBMC+IL2 (p < 0.01), PBMC+PC (p < 0.001), and PBMC+G2 (p < 0.001) groups. Here, IL2 is linked to colorectal carcinoma.