Finally, 18 common critical proteins, i.e. AKT1, BCL2L1, CCND1, CDH1, CDKN2A, CTNNB1, EGF, EGFR, ERBB2, HRAS, IL6, JUN, KRAS, NOTCH1, SNAI1, STAT3, TNF, and TP53, remained as the core proteins of the three types of cancers. The gene discussed is HRAS; the disease is cancer.