Finally, 18 common critical proteins, i.e. AKT1, BCL2L1, CCND1, CDH1, CDKN2A, CTNNB1, EGF, EGFR, ERBB2, HRAS, IL6, JUN, KRAS, NOTCH1, SNAI1, STAT3, TNF, and TP53, remained as the core proteins of the three types of cancers. Here, ERBB2 is linked to cancer.