IL1B and microcytic anemia: CRC patients with microcytic anemia (MCV < 83fL) had significantly higher IL-33 (p = 0.009), Gal-1 (p = 0.002) and IL-1 (p = 0.013) in sera in comparison to CRC patients with normocytic anemia or without anemia (Figure 4B, Figure 4C, Figure 4D).