TRPV1 and serum lipopolysaccharide activity: We determined the role of neuronal TRPV1 in the anti-inflammatory actions of OLDA in endotoxemia by comparing responses of mice with pan-neuronal TRPV1 knockdown that were produced by breeding BAF53b-Cre+/− mice [55], with Trpv1lox/lox mice to generate BAF53b-Cre+/−/Trpv1lox/lox mice with control BAF53b-Cre−/−/Trpv1lox/lox mice with normal TRPV1 expression.