Therefore, we verified the expression of Th1/Th2 cell-associated chemokines by RT-qPCR.7-Met decreased the transcription of Th1 cell-associated chemokines (Cxcl9 and Cxcl10) and Th2 cell-associated chemokines (Ccl17 and Ccl22) in FITC-induced AD mice model (Fig. 5b,c). This evidence concerns the gene CCL22 and Alzheimer disease.