Typicality was significantly associated with the presence of (1) tau in the dentate gyrus; (2) α-syn in the parahippocampal gyrus; (3) TDP-43 in the parahippocampal gyrus, dentate gyrus, entorhinal cortex, amygdala, and superior/middle temporal gyri; and (4) concomitance of the AD and non-AD pathologies. Here, TARDBP is linked to Alzheimer disease.