ASCL2 and polyp: Comparing tuft cells to all other cell types, we identified a set of tuft cell markers common to both polyp patients and controls, including ASCL2, POU2F3, and AVIL, which we call “common markers.” Then, comparing tuft cells from control versus polyp patients, we identified a second set of genes increased in the tuft cells of polyp patients, including BMX, GNG13, TRPM5, and PTGS1, which we call “polyp tuft markers” (Figure 1F).