Next, we conducted a logistic regression analysis based on univariate analysis, which shows that the proportion of CD8+ Tn cells (P < 0.05), LD CD4+ T cells (P < 0.05), and ED CD8+ T cells are associated with PD condition, after adjustment for confounding factors, such as diabetes mellitus status, smoking consumption, alcohol consumption, and tea consumption (Table 2). Here, CD8A is linked to diabetes mellitus.