CD8A and Parkinson disease: Next, we conducted a logistic regression analysis based on univariate analysis, which shows that the proportion of CD8+ Tn cells (P < 0.05), LD CD4+ T cells (P < 0.05), and ED CD8+ T cells are associated with PD condition, after adjustment for confounding factors, such as diabetes mellitus status, smoking consumption, alcohol consumption, and tea consumption (Table 2).