PARP12 and cancer: Indeed,several PARylated nuclear proteins move to the cytoplasm where theyinteract with the PARP12 WWE domain, thus promoting the PARP12 accumulationin cytoplasmic stress granules.129,140 Herein, PARP12regulates mRNA translation and stability as a response to a stressconditions.129 This translocation is, however,a reversible condition, and after the stress response, PARP12 relocalizesin the Golgi complex.141 PARP12 ADP-ribosylatesGolgin-97 thereby regulates the basolateral transport of proteins.142 The function of PARP12 in cancer remains highlycontroversial.