Another important role of PARP7 has been recently identified alsoin ovarian cancer, in which PARP7 contributes to the cancer proliferation.Indeed, PARP7 MARylated various cytoskeletal proteins, including α-tubulin,thus facilitating cell growth; when PARP7 was depleted, a reductionin cancer cell growth is observed.156. The gene discussed is TIPARP; the disease is ovarian carcinoma.