ALB and nutritional deficiency disease: Extraintestinal manifestations in children with IBD, growth retardation, aphthous ulcers, arthropathy, oculopathy, and skin lesions are common, and all of them are associated with immune-mediated pathogenesis.[28,29] Since malnutrition and growth retardation are important issues in pediatric CD, Song et al[30] investigated the prevalence of nutritional and growth status in Korean children with CD and found subnormal serum levels of hemoglobin, albumin, iron, ferritin, calcium, magnesium, folate, vitamin B12, and zinc.