GSDMD and Salmonella Infections: In neutrophils, non-canonical inflammasome activity and GSDMD targeting of the nuclear membrane results in neutrophil extracellular trap formation to control Salmonella infection [80], while in macrophages it has been reported that both non-canonical and canonical inflammasome signaling and GSDMD pore formation causes calcium ion influx to allow for IL-1α maturation [81].