As clarified by current reports, EGFR ex20ins was associated with much lower levels of TMB (2.8–3.6/Muts/Mb) than WT EGFR, as well as with a low TPS of PD‐L1 expression, which suggested lack of comparable benefit of ICI in EGFR ex20ins as observed in NSCLC harboring common EGFR mutations.10, 21, 22, 33. This evidence concerns the gene EGFR and non-small cell lung carcinoma.