FHL1 and Emery-Dreifuss muscular dystrophy: Since then, 11 new FHL1 variants have been reported to cause EDMD (Giucă et al., 2020; Gossios et al., 2013; Malfatti et al., 2013; Pen et al., 2015; San Román et al., 2016; Tiffin et al., 2013; Willis et al., 2016), almost all with a severe phenotype and all with some residual expression of FHL1 proteins.