In the TCGA lung adenocarcinoma, LUAD VIM-AS1 is divided into the high expression and low expression in the two groups after the present common gene expression differences, and high VIM-AS1 gene expression related genes CCDC37, ZMYND10, TTC16, DLEC1, and TTLL9; genes associated with low expression of VIM-AS1 include S100P, INSL4, GPX2, F2, and CA12 (Figure 3). Here, TTC16 is linked to lung adenocarcinoma.