The top-ranking pathways enriched in the shared genes include “ECM-receptor interaction” (FRAS1/SPP1, P value = 4.92e-03), “growth hormone synthesis, secretion and action” (ADCY5/SOCS3, P value = 8.84e-03) and “type II diabetes mellitus” (SOCS3, P value = 0.055). The gene discussed is SOCS3; the disease is type 2 diabetes mellitus.