SNCA and Lewy body dementia: Previous studies have only shown modest thalamic pathology resulting from intrastriatal PFF injection at 90 days p.i. [35], and hippocampal pathology is not typically reported except upon direct intrahippocampal injection in synuclein transgenic mice [53], or 15 months post-intranigral injection of fibrils isolated from DLB patients [40], or upon internal capsule/caudate putamen injection of synuclein transgenic mice [58].