In this study, the roles of 23 m6A modification regulators (“readers”: IGF2BP1, IGF2BP2, IGF2BP3, YTHDC1, YTHDC2, YTHDF1, YTHDF2, YTHDF3 ELAVL1, FMR1, HNRNPA2B1, HNRNPC, and LRPPRC; “erasers”: ALKBH5 and FTO; and “writers”: CBLL1, KIAA1429, METTL3, METTL14, RBM15, RBM15B, WTAP, and ZC3H13) were investigated in pancreatic cancer. This evidence concerns the gene YTHDF1 and familial pancreatic carcinoma.