KCNA5 and pulmonary arterial hypertension: Pozeg et al. showed that tracheal delivery of nebulised replication-deficient HAd-5 Kv1.5 (encodes Kv1.5 potassium channel, an O2-sensitive channel which is downregulated in chronic pulmonary hypoxia) normalised pulmonary vascular constriction/resistance in a rat model of PAH [189].